Search results for " N-methyl-2-pyrrolidone"

showing 6 items of 6 documents

CCDC 1945329: Experimental Crystal Structure Determination

2020

Related Article: Agris Be̅rziņš, Artis Kons, Kristaps Saršu̅ns, Sergey Belyakov, Andris Actiņš|2020|Cryst.Growth Des.|20|5767|doi:10.1021/acs.cgd.0c00331

2-chloro-4-nitrobenzoic acid N-methyl-2-pyrrolidone solvateSpace GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

In vitro evaluation of poloxamer in situ forming gels for bedaquiline fumarate salt and pharmacokinetics following intramuscular injection in rats

2019

Graphical abstract

In situPO Propylene oxideIV IntravenousP338 Poloxamer 338lcsh:RS1-441Pharmaceutical Sciencechemistry.chemical_compoundn Sample sizeSD Standard deviationIM Intramuscularchemistry.chemical_classificationC0 Analyte plasma concentration at time zeroDoE Design of experimentsUV UltravioletPharmacology. TherapyK2.EDTA Potassium ethylenediaminetetraacetic acidLC–MS/MS Liquid chromatography-tandem mass spectrometryH&E Hematoxylin and eosintmax Sampling time to reach the maximum observed analyte plasma concentrationIn situ forming gelsCMC Critical micellar concentrationCmax Maximum observed analyte plasma concentrationIntramuscular injectionDN Dose normalizedGPT Gel point temperaturePLGA Poly-(DL-lactic-co-glycolic acid)TFA Trifluoroacetic acidCAN AcetonitrileATP Adenosine 5′ triphosphateSalt (chemistry)Polyethylene glycolPoloxamerArticlelcsh:Pharmacy and materia medicaPharmacokineticsIn vivoUHPLC Ultra-high performance liquid chromatographyPharmacokineticsAUClast Area under the analyte concentration versus time curve from time zero to the time of the last measurable (non-below quantification level) concentrationEO Ethylene oxideNMP N-methyl-2-pyrrolidoneComputingMethodologies_COMPUTERGRAPHICSAUC∞ Area under the analyte concentration vs time curve from time zero to infinite timeP407 Poloxamer 407In vitro releasePoloxamerCMT Critical micellar temperatureGel erosionIn vitrot1/2 Apparent terminal elimination half-lifechemistryMDR-TB Multi-drug resistant tuberculosisAUC80h Area under the analyte concentration versus time curve from time zero to 80 htlast Sampling time until the last measurable (non-below quantification level) analyte plasma concentrationMRM Multiple reaction monitoringNuclear chemistrySustained releaseInternational Journal of Pharmaceutics: X
researchProduct

CCDC 1945318: Experimental Crystal Structure Determination

2020

Related Article: Agris Be̅rziņš, Artis Kons, Kristaps Saršu̅ns, Sergey Belyakov, Andris Actiņš|2020|Cryst.Growth Des.|20|5767|doi:10.1021/acs.cgd.0c00331

Space GroupCrystallography2-methyl-4-nitrobenzoic acid N-methyl-2-pyrrolidone solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1945336: Experimental Crystal Structure Determination

2020

Related Article: Agris Be̅rziņš, Artis Kons, Kristaps Saršu̅ns, Sergey Belyakov, Andris Actiņš|2020|Cryst.Growth Des.|20|5767|doi:10.1021/acs.cgd.0c00331

Space GroupCrystallography4-chloro-3-nitrobenzoic acid N-methyl-2-pyrrolidone solvateCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1945321: Experimental Crystal Structure Determination

2020

Related Article: Agris Be̅rziņš, Artis Kons, Kristaps Saršu̅ns, Sergey Belyakov, Andris Actiņš|2020|Cryst.Growth Des.|20|5767|doi:10.1021/acs.cgd.0c00331

Space GroupCrystallographyCrystal SystemCrystal Structure5-chloro-2-nitrobenzoic acid N-methyl-2-pyrrolidone solvateCell ParametersExperimental 3D Coordinates
researchProduct

CCDC 1945333: Experimental Crystal Structure Determination

2020

Related Article: Agris Be̅rziņš, Artis Kons, Kristaps Saršu̅ns, Sergey Belyakov, Andris Actiņš|2020|Cryst.Growth Des.|20|5767|doi:10.1021/acs.cgd.0c00331

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters2-hydroxy-4-nitrobenzoic acid N-methyl-2-pyrrolidone solvateExperimental 3D Coordinates
researchProduct